The metabolism of lysergic acid diethylamide.

نویسنده

E S BOYD

چکیده

The unavailability of a suitable preanaesthetic medicament is discussed. A double blind comparison of placebo, meprobamate and pentobarbital as preanaesthetic medicants for regional procedures is presented. The authors have determined the effects of each of these treatments on patient's apprehension, cooperation, drowsiness, reaction to painful stimuli, talkativeness, nausea and emesis. The anaesthetist's evaluation of the adequency of each premedicant has also been determined. Both, meprobamate and pentobarbital have been found to be more effective than placebo. The difference is well marked in younger group of patients but tends to be less marked with advancing age and may disappear in the senile group. No significant difference has been found between meprobamate and pentobarbital in doses employed.

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